I am from Asia and my white husband is from the deep south of USA and we're living in his hometown. We are married for almost 15 years and are blessed with 4 most beautiful interracial children. I think the best that comes out of a interracial couple are the kids will get the best of both world.
Yes, I first have to say that in the beginning it is not easy. I feel homesick - for my family, my culture, food, language etc but since I chose to marry and follow my husband, it is sink or swim for me. I know many women who hated it here and want to go home. But I have to be mature about it. If his family or friends do not understand my accent or my culture, I try to explain and even learn to laugh about it. I have to make friends and the only way is to approach them. I need them, they don't need me. So I tried to adjust as much as I could. I also have a very supportive husband that tries to learn my culture and let me decorate the house or raise the kids as Asian as I can. It is a give and take.
I think another thing is to help your foreign spouse find as many other people that are same nationality as her. She will feel less homesick and now she will have friends that understands what she is going through.
My kids sadly got teased too by their schoolmates. They were all born Americans but many people asked where do they come from, if they are adopted, if they eat dogs, cats, snakes or other human beings ???!!! Kids can be so cruel. I told my kids to ignore ignorant people. I, like most Asians were raised with just eating chicken or fish but thanks to some international cooking show, Asians have bad reputations that is simply not true. My kids have support system from other American born Asian kids, so they can learn to handle people better. Hope this helps.
I feel like I am an 'ambassador' of my people to this country. I have to educate people who don't know anything outside of their 4 walls. I have people thinking that Asia is a country (it is a continent) and there are like hundreds or thousands languages and dialects there. Now folks are amazed that my kids and I can speak other lauguages and want us to teach them. They also say that they like our hot and spicy food. Also, after knowing me for so many years, I have many true American white, black and hispanic friends. When they talk to me, they see my heart, not my skin color. I know, once they know the real me, they will be less prejudice against the next Asian they meet. My husband and I are like pioneers for all other white/asian couple in the future that might comes along. :-)